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United States Reissued Patent USRE42645 (E) Drakulic T, Temple MD, Guido R, Jarolim S, Breitenbach M, Attfield PV, Dawes IW (2005) Involvement of oxidative stress response genes in redox homeostasis, the level of reactive oxygen species, and ageing in Saccharomyces cerevisiae

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Parallel genomic alterations of antigen and payload targets mediate polyclonal acquired clinical resistance to sacituzumab govitecan in triple-negative breast cancer

Although product aggregates are formed intracellularly, traditional process development strategies to mitigate product aggregation focus on extracellular parameters (pH, temperature, DO etc.), virtually ignoring their effects on the intracellular environment 6,7

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(2019c)